Today we announce the publication of the Oral History Center’s interviews with Dr. Stan Glantz. Dr. Glantz received his doctorate in applied mechanics from Stanford University before embarking on a multi-decade career at UC San Francisco. He contributed engineering concepts to cardiovascular research, biostatistics to epidemiology, and economics to the study of second-hand smoke and policymaking to regulate second-hand smoke, among many other research projects. The oral history explores his political and policy activism, the history of the clean indoor air movement, and his commitments to science and public health, in particular his long struggles with the tobacco industry and efforts to make UC San Francisco a world center for research into second-hand smoke, nicotine addiction, and the broader social determinants of health. His service to UC San Francisco and the University of California is also explored, in particular, his research and advocacy for policy changes on issues ranging from the rights of adjunct faculty to state funding of the UC system. These interviews showcase Glantz’s applied epistemology, his continual reflection on how knowledge is produced and shaped through formal and informal practices for arriving at scientific truth.