This oral history with Randy Schekman is one in a series documenting bioscience and biotechnology in Northern California. Schekman’s research investigates fundamental cellular processes at the molecular, biochemical, and genetic levels. In the interviews, he describes the work which illuminates the mechanism and control of the complex intracellular pathways by which proteins are transported within the living cell. It was this body of research which led to the highest honors in biology, the Lasker Award in Basic Medical Research in 2002 and the Nobel Prize in Physiology or Medicine in 2013. Interviews conducted by Sally Smith Hughes in 2014.